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Mar 3, 2018 · Jurkat细胞模型在丙型肝炎病毒感染研究中的应用. 丙型肝炎由丙型肝炎病毒 (hepatitis C virus, HCV)主要通过血液传播, 机体免疫难以有效清除病毒。HCV核心蛋白可影响宿主细胞凋亡和免疫系统的功能, 在HCV感染的病理发生、慢性化以及宿主细胞的恶性转化等过程中起 ...

Jan 4, 2019 · Inhibition of DDR1 activity by DDR1-specific inhibitor DDR-IN-1 accelerated cell death in the presence of Ara-C, DNR or their combination. These results demonstrated that 3D culture enhances chemoresistance of ALL Jurkat cell line by increasing DDR1 expression. Importantly, the cell adhesion-mediated drug resistance induced by DDR1 in the ...

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